NCT03448926
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This study is looking at how a specific genetic test, called DCISionRT, helps doctors and patients make decisions about treating ductal carcinoma in situ, often referred to as DCIS or Stage 0 breast cancer. DCISionRT looks at seven different genes in your tumor tissue to predict the risk of the cancer returning and whether radiation therapy is likely to be beneficial for you. Because this is an observational study, it does not change the medical care you receive. Instead, researchers will ask your doctor to complete surveys before and after they see your test results to see if the information changed your recommended treatment plan.
To be eligible, you must be between 30 and 85 years old and have a recent diagnosis of DCIS in one breast that is smaller than six centimeters. You must be a candidate for breast-conserving surgery, such as a lumpectomy, and be eligible for radiation or hormone therapy. Patients who have already had a mastectomy, those with invasive breast cancer, or those who have had breast cancer in the past are not eligible. Participation primarily involves allowing your medical team to share your test results and treatment plans with the research team. Before enrolling, you should talk with your doctor about whether the DCISionRT test is appropriate for your diagnosis and how the results might influence your options for surgery or radiation.
Generated · Written by an AI model from the trial’s public ClinicalTrials.gov record. Not medical advice.
This is a prospective, non-interventional (observational) cohort study conducted within the medical network of the participating investigators and institutions. Patients meeting the eligibility criteria (see below) will be eligible for participation and the investigators will obtain written informed consent. A central Institutional Review Board (IRB), WCG IRB, will approve the protocol and each participating institution.
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Arizona Center for Cancer Care
Scottsdale, Arizona
Penny Labriola · 480-278-8261 · penny.labriola@arizonaccc.com
University of California San Diego
La Jolla, California
Sauntee Braddock · 858-822-6040 · sbraddock@health.ucsd.edu
Sutter Health
San Mateo, California
Silvia Gonzalez · 650-696-4814 · silvia.gonzalez3@sutterhealth.org
University of Colorado Anschutz Medical Campus
Aurora, Colorado
Chitra Pai-Kulyadi · 857-919-8557 · chitra.paikulyadi@cuanschutz.edu
Baptist MD Anderson Cancer Center
Jacksonville, Florida
Austin Anderson · 904-202-7501 · austin.anderson@bmcjax.com